Generic
Triazolam
Brand Name
Halcion
Import ID
237
Triazolam
| Interaction Color Code | Clinical Bottom Line | Clinical Effects | Drug 1 effect | Drug 2 dose | Drug 2 effect | Management | |
|---|---|---|---|---|---|---|---|
| Lenacapavir Triazolam | Yellow: Adjust dosing | Minimal data to guide interaction: weigh risks and benefits of using this combination | Increased risk of triazolam adverse effects |
If coadministering, monitor for triazolam adverse effects (e.g. sedation, respiratory depression). |
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| Ritonavir Triazolam 1072 | Red: Avoid combination | Do not coadminister: Increased levels of triazolam | Increased triazolam effects (eg, increased confusion, sedation, respiratory depression) |
0.125 mg x 1 dose | Triazolam AUC increased 1939%; half-life: increased 1267%; Cmax increased 87% |
Use alternative agents |
|
| Darunavir Triazolam 945 | Red: Avoid combination | Do not coadminister: Potential for increased levels of triazolam | Potential for increased risk of triazolam adverse effects (e.g. increased sedation, confusion, respiratory depression) |
Contraindicated. Use alternative agents. |
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| Atazanavir Triazolam 820 | Red: Avoid combination | Do not coadminister: Potential for increased levels of triazolam | Potential for increased triazolam adverse effects (eg, increased sedation, confusion, respiratory depression) |
Contraindicated. Use alternative agents. |
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| Efavirenz Triazolam 482 | Orange: Minimal data to guide interaction | Minimal data to guide interaction: risks likely to outweigh benefits | Increased triazolam effects (eg, increased sedation, confusion, respiratory depression) |
Not studied |
Not studied (may increase triazolam levels) |
Avoid combination and use alternative agents |
|
| Elvitegravir Triazolam 202 | Red: Avoid combination | Do not coadminister: Potential for increased levels of triazolam | Potential for increased triazolam effects (e.g. prolonged sedation, altered mental status, respiratory depression) |
Contraindicated. Use alternative agents. |
