Interaction Color Code
Clinical Bottom Line
Do not coadminister: Increased levels of triazolam
Drug 1
Drug 1 dose
200 mg BID x 2 days
Drug 2
Drug 2 dose
0.125 mg x 1 dose
Drug 2 effect
Triazolam AUC increased 1939%; half-life: increased 1267%; Cmax increased 87%
Clinical Effects
Increased triazolam effects (eg, increased confusion, sedation, respiratory depression)
Management
Use alternative agents
Alternative Agents
Lorazepam, Oxazepam, Temazepam, Trazodone
Import ID
1072
