Generic
Vardenafil
Brand Name
Levitra
Import ID
145
Vardenafil
| Interaction Color Code | Clinical Bottom Line | Clinical Effects | Drug 1 effect | Drug 2 dose | Drug 2 effect | Management | |
|---|---|---|---|---|---|---|---|
| Lenacapavir Vardenafil | Yellow: Adjust dosing | Minimal data to guide interaction: weigh risks and benefits of using this combination | Increased risk of vardenafil adverse effects (e.g. flushing, headache, hypotension) |
If co-administering vardenafil for erectile dysfunction, dose should not exceed 5 mg per 24 hour. Monitor for adverse effects. |
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| Ritonavir Vardenafil 1049 | Yellow: Adjust dosing | Adjust dosing to avoid increased levels of vardenafil | Increased tadalafil effects |
5 mg daily | Vardenafil AUC increased 49-fold; Cmax increased 13-fold. T1 / 2 increased to 26 hours. |
Initiate (and do not exceed) vardenafil 2.5 mg every 72 hours and monitor for adverse effects |
|
| Darunavir Vardenafil 892 | Yellow: Adjust dosing | Adjust dosing to avoid increased levels of vardenafil | Increased risk of vardenafil adverse effects (e.g. hypotension, priapism) |
Do not exceed 2.5 mg dose in 72 hours |
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| Elvitegravir Vardenafil 177 | Yellow: Adjust dosing | Adjust dosing to avoid increased levels of vardenafil | Potential for increased vardenafil effects (e.g. hypotension, priapism) |
Initiate vardenafil 2.5 mg every 72 hours and monitor for adverse effects |
