Interaction Color Code
Clinical Bottom Line
Adjust dosing to avoid increased levels of vardenafil
Drug 1
Drug 1 dose
600 mg BID
Drug 2
Drug 2 dose
5 mg daily
Drug 2 effect
Vardenafil AUC increased 49-fold; Cmax increased 13-fold. T1 / 2 increased to 26 hours.
Clinical Effects
Increased tadalafil effects
Management
Initiate (and do not exceed) vardenafil 2.5 mg every 72 hours and monitor for adverse effects
Import ID
1049
