Dronedarone
| Interaction Color Code | Clinical Bottom Line | Clinical Effects | Drug 1 effect | Drug 2 dose | Drug 2 effect | Management | |
|---|---|---|---|---|---|---|---|
| Lenacapavir Dronedarone | Yellow: Adjust dosing | Minimal data to guide interaction: weigh risks and benefits of using this combination | Potential increased risk of dronedarone adverse effects |
Consider using alternative cardiac medication or ARV. If coadministering, monitor for dronedarone adverse effects. |
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| Darunavir Dronedarone 927 | Red: Avoid combination | Do not coadminister: Potential for increased dronedarone levels | Potential for increased risk of dronedarone adverse effects |
Use alternative agents |
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| Elvitegravir Dronedarone 246 | Orange: Minimal data to guide interaction | Minimal data to guide interaction: weigh risks and benefits of using this combination | Potential for increased risk of dronedarone adverse effects |
If coadministering monitor for dronedarone toxicity. Consider therapeutic drug monitoring and ECG. |

