DHHS Adult ARV Guidelines
Interaction Color Code
Clinical Bottom Line
Minimal data to guide interaction: weigh risks and benefits of using this combination
Drug 1
Drug 2
Mechanism
Inhibition of CYP3A4 by lenacapavir
Clinical Effects
Potential increased risk of dronedarone adverse effects
Management
Consider using alternative cardiac medication or ARV. If coadministering, monitor for dronedarone adverse effects.
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