| Interaction Color Code | Clinical Bottom Line | Clinical Effects | Drug 1 effect | Drug 2 dose | Drug 2 effect | Management | |
|---|---|---|---|---|---|---|---|
| Darunavir Dextromethrophan 1030 | Orange: Minimal data to guide interaction | Minimal data to guide interaction: weigh risks and benefits of using this combination | Potential for increased dextromethorphan effects |
Not reported |
30 mg x 1 | Cmax increase 127%, AUC increase 170% |
Monitor for dextromethorphan adverse effects |
