Darunavir Dextromethrophan 1030

Prezista label

Clinical Bottom Line
Minimal data to guide interaction: weigh risks and benefits of using this combination
Drug 1
Drug 1 dose
600 mg with 100 mg ritonavir BID
Drug 1 effect

Not reported

Drug 2 dose
30 mg x 1
Drug 2 effect

Cmax increase 127%, AUC increase 170%

Clinical Effects

Potential for increased dextromethorphan effects

Management

Monitor for dextromethorphan adverse effects

Import ID
1030