| Interaction Color Code | Clinical Bottom Line | Clinical Effects | Drug 1 effect | Drug 2 dose | Drug 2 effect | Management | |
|---|---|---|---|---|---|---|---|
| Ritonavir Olanzapine 1035 | Yellow: Adjust dosing | Adjust dosing to avoid decreased levels of olanzapine | Decreased olanzapine effects |
Not studied |
10 mg daily | Olanzapine AUC decreased 53%; half-life: decreased 50%; clearance: increased 115%; Cmax decreased 40% |
Monitor clinical improvement and adjust olanzapine as indicated |
