Meperidine

Drug Class or Subclass

Generic

Meperidine

Brand Name

Demerol

Import ID

9

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	Interaction Color Code	Clinical Bottom Line	Clinical Effects	Drug 1 effect	Drug 2 dose	Drug 2 effect	Management
Ritonavir Meperidine 1100	Orange: Minimal data to guide interaction	Minimal data to guide interaction: weigh risks and benefits of using this combination	Increased normeperidine effects		50 mg PO x 1 dose	Meperidine AUC decreased 67%; normeperidine AUC increased 47%	If coadministering monitor for pain control and adjust dose as indicated

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