Lenacapavir Thioridazine

DHHS Adult ARV Guidelines

Interaction Color Code
Clinical Bottom Line
Minimal data to guide interaction: risks likely to outweigh benefits
Drug 1
Drug 2
Mechanism
Inhibition of CYP3A4 by lenacapavir, induction of CYP3A by thioridazine
Clinical Effects

Potential loss of antiviral efficacy

Management

Consider using alternative antipsychotic