Interaction Color Code
Clinical Bottom Line
Do not coadminister: Increased levels of fluticasone
Drug 1
Drug 1 dose
100 mg BID x 7 days
Drug 2
Drug 2 dose
200 mcg once daily x 7 d
Drug 2 effect
Fluticasone Cmax increased 2572%; AUC increased 36697%
Clinical Effects
Increased fluticasone effects (eg, Cushing's syndrome, adrenal suppression)
Management
Avoid combination and use alternative agents
Import ID
1071
