Prezista label
Interaction Color Code
Clinical Bottom Line
Adjust dosing to avoid reduced levels of warfarin
Drug 1
Drug 1 dose
600 mg with 100 mg ritonavir BID
Drug 1 effect
Not reported
Drug 2
Drug 2 dose
10 mg x 1
Drug 2 effect
S-warfarin Cmax decrease 8%, AUC decrease 21%
Clinical Effects
Decreased warfarin effects (e.g. decreased INR, increased risk of clotting)
Management
If coadministering, monitor INR and adjust warfarin as indicated. Monitor for signs and symptons of bleeding.
Import ID
899
