Prezista label
Interaction Color Code
Clinical Bottom Line
Adjust dosing to avoid increased levels of digoxin
Drug 1
Drug 1 dose
600 mg with 100 mg ritonavir BID
Drug 1 effect
Not reported
Drug 2
Drug 2 dose
0.4 mg x 1
Drug 2 effect
Cmax increase 15%, AUC increase 36%
Clinical Effects
Increased risk of digoxin adverse effects
Management
Initiate lowest dose digoxin and titrate to desired clinical effect
Import ID
882
