Interaction Color Code
Clinical Bottom Line
Administer standard doses
Drug 1 dose
300 mg once daily
Drug 1 effect
Cmax increase 19%, AUC increase 23%, Cmin increase 24%
Drug 2
Drug 2 dose
150 mg once daily
Drug 2 effect
No significant change
Clinical Effects
Potentially increased risk of TDF adverse effects
Management
Use recommended dose of rilpivirine 25 mg
Import ID
730
