Interaction Color Code
Clinical Bottom Line
Adjust dosing to avoid reduced levels of rilpivirine
Drug 1
Drug 1 dose
150 mg x 1
Drug 1 effect
Rilpivirine AUC decreased 76%; Cmax decreased 85%
Drug 2
Drug 2 dose
40 mg x 1 taken 2 hours before rilpivirine
Clinical Effects
Decreased rilpivirine effects
Management
Administer H2-antagonist by at least 12 hours before rilpivirine or at least 4 hours after rilpivirine.
Import ID
646
