Interaction Color Code
Clinical Bottom Line
Do not coadminister: Reduced levels of arthemether / lumifantrine
Drug 1
Drug 2
Drug 2 dose
artemether / lumefantrine 80 mg / 480 mg x 6 doses
Drug 2 effect
Lumefantrine AUC increased 56%; Cmax increased 24%; half-life: no significant change; clearance: decreased 36%
Management
Use alternative agents
Import ID
612
