Interaction Color Code
Clinical Bottom Line
Adjust dosing to avoid reduced levels of daclatasvir
Drug 1
Drug 1 dose
200 mg daily x 14 days; 200 mg
Drug 1 effect
Nevirapine Cmin decreased 16%
Drug 2
Drug 2 effect
Not studied (may decrease daclatasvir levels)
Clinical Effects
Potential loss of anti-HCV efficacy
Management
Increase daclatasvir dose to 90 mg daily.
Import ID
576
