Interaction Color Code
Clinical Bottom Line
Minimal data to guide interaction: risks likely to outweigh benefits
Drug 1
Drug 1 dose
200 mg BID
Drug 1 effect
No significant change
Drug 2
Drug 2 dose
artemether / lumefantrine 80 / 480 mg
Drug 2 effect
Artemether AUC decreased 38%; Lumefantrine AUC decreased 13%
Clinical Effects
Decreased antimalarial effects
Management
Use with caution; avoid if possible
Import ID
562
