Interaction Color Code
Clinical Bottom Line
Do not coadminister: Potential for increased levels of ergotamine
Drug 1
Drug 1 effect
Not studied
Drug 2
Drug 2 effect
Not studied (may increase ergotamine levels)
Clinical Effects
Potentially increased ergotamine effects (eg, ergotism)
Management
Avoid combination and use alternative agents
Alternative Agents
Depending on indication, 5-HT agonists ("triptans"), prostaglandin F2, misoprostol or oxytocin may be an option. Clinical induction effects may lower clinical response to methylergonovine.
Import ID
432
