Interaction Color Code
Clinical Bottom Line
Administer standard doses
Drug 1
Drug 1 dose
600 mg daily x 14 days
Drug 1 effect
No significant change
Drug 2
Drug 2 dose
50 mg daily x 14 days
Drug 2 effect
Sertaline AUC decreased 39%, Cmax decreased 29%, Cmin decreased 46%
Clinical Effects
Decreased sertaline effects
Management
Monitor for signs and symptoms of depression and titrate sertaline to effect
Import ID
401
