Interaction Color Code
Clinical Bottom Line
Administer standard doses
Drug 1
Drug 1 dose
600 mg QHS
Drug 2
Drug 2 dose
150 mg SR x 1
Drug 2 effect
Bupropion AUC decreased 55%; Cmax decreased 34%; half-life: decreased 46%
Clinical Effects
Decreased bupropion effects
Management
Monitor for signs and symptoms of depression and titrate bupropion to effect
Import ID
399
