Interaction Color Code
Clinical Bottom Line
Minimal data to guide interaction: risks likely to outweigh benefits
Drug 1
Drug 2
Clinical Effects
Potential for increased risk of bleeding
Management
Consider avoiding combination and using alternative anticoagulant. If coadministering, reduce apixaban dose by 50% in patients who require 5-10 mg twice daily. Do not coadminister in persons who require apixaban 2.5mg twice daily.
Import ID
224
