package insert
Interaction Color Code
Clinical Bottom Line
Adjust dosing to avoid increased levels of desipramine
Drug 1
Drug 1 dose
150 mg cobicistat once daily (no elvitegravir)
Drug 1 effect
Not reported
Drug 2
Drug 2 dose
50 mg single dose
Drug 2 effect
Cmax increased 24%, AUC increased 65%
Clinical Effects
Increased desipramine effects
Management
If coadministering, initiate low dose desipramine and titrate according to efficacy and adverse effects.
Import ID
125
