| Interaction Color Code | Clinical Bottom Line | Clinical Effects | Drug 1 effect | Drug 2 dose | Drug 2 effect | Management | |
|---|---|---|---|---|---|---|---|
| Lencapavir Alfuzosin | Yellow: Adjust dosing | Minimal data to guide interaction: weigh risks and benefits of using this combination | Potential for increased alfuzosin effects |
Consider alternative to alfuzosin. If coadministered, monitor for adverse effects (e.g. hypotension) |
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| Ritonavir Alfuzosin 1076 | Red: Avoid combination | Do not coadminister: Potential for increased levels of alfuzosin | Not studied |
Not studied (may increase alfuzosin levels) |
Use alternative agents |
||
| Darunavir Alfuzosin 934 | Red: Avoid combination | Do not coadminister: Potential for increased levels of alfuzosin | Potential for increased risk of alfuzosin adverse effects (e.g. hypotension) |
Contraindicated. Use alternative agents. |
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| Atazanavir Alfuzosin 817 | Red: Avoid combination | Do not coadminister: Increased levels of alfuzosin | Contraindicated. Use alternative agents. |
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| Elvitegravir Alfuzosin 185 | Red: Avoid combination | Do not coadminister: Potential for increased levels of alfuzosin | Potential for increased alfuzosin adverse effects (e.g. hypotension) |
Contraindicated. Use alternative agents. |
