Hydrocortisone

Drug Class or Subclass

Generic

Hydrocortisone

Brand Name

Hydrocort, Alphosyl, Aquacort, Cortef, Cortenema, Solu-Cortef

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	Interaction Color Code	Clinical Bottom Line	Clinical Effects	Drug 1 effect	Drug 2 dose	Drug 2 effect	Management
Lenacapavir Hydrocortisone	Yellow: Adjust dosing	Minimal data to guide interaction: weigh risks and benefits of using this combination	Potential increased risk of corticosteroid adverse effects (e.g. Cushing's syndrome and adrenal supression).				If co-administering, initiate with the lowest starting dose and titrate to clinical effect. Monitor for hydrocortisone-related adverse effects.