Drug Class or Subclass
Generic
Cobicistat
Brand Name
Tybost
Cobicistat
| Interaction Color Code | Clinical Bottom Line | Clinical Effects | Drug 1 effect | Drug 2 dose | Drug 2 effect | Management | |
|---|---|---|---|---|---|---|---|
| Lenacapavir Cobicistat | Yellow: Adjust dosing | Minimal data to guide interaction: weigh risks and benefits of using this combination | Increased risk of lenacapavir adverse effects |
AUC increased 128%; Cmax increased 110% |
150 mg once daily (in fed state) | Not reported |
Management of interaction depends on component that cobicistat is serving as a PK booster for. See partner antiretroviral for further details. |
