Generic
Diazepam
Brand Name
Valium
Import ID
230
Diazepam
| Interaction Color Code | Clinical Bottom Line | Clinical Effects | Drug 1 effect | Drug 2 dose | Drug 2 effect | Management | |
|---|---|---|---|---|---|---|---|
| Lenacapavir Diazepam | Yellow: Adjust dosing | Minimal data to guide interaction: weigh risks and benefits of using this combination | Potential increased risk of sedation, respiratory depression |
Consider alternative benzodiazepines. If coadministering, use lowest effective dose and monitor for diazepam adverse effects. |
|||
| Ritonavir Diazepam 1095 | Orange: Minimal data to guide interaction | Minimal data to guide interaction: risks likely to outweigh benefits | Increased diazepam effects (eg, increased sedation, confusion, respiratory depression) |
Not studied |
Increased diazepam levels |
Use alternative agents |
|
| Darunavir Diazepam 1008 | Orange: Minimal data to guide interaction | Minimal data to guide interaction: weigh risks and benefits of using this combination | Potential for increased risk of diazepam adverse effects |
If coadministering, initiate diazepam at low dose and titrate to effect |
|||
| Elvitegravir Diazepam 250 | Orange: Minimal data to guide interaction | Minimal data to guide interaction: weigh risks and benefits of using this combination | Potential for increased risk of sedative-hypnotic adverse effects |
If coadministering start with low dose and titrate accordingly. Monitor for side effects. |
