Enzalutamide
| Interaction Color Code | Clinical Bottom Line | Clinical Effects | Drug 1 effect | Drug 2 dose | Drug 2 effect | Management | |
|---|---|---|---|---|---|---|---|
| Doravirine Enzalutamide 348 | Red: Avoid combination | Do not coadminister: Potential for reduced levels of doravirine | Potential decrease in antiretroviral efficacy |
Contraindicated. Use alternative agents. If discontinuing enzalutamide, a minimum 4 week cessation period is recommended prior to initiating doravirine. |
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| Cabotegravir Enzalutamide 334 | Red: Avoid combination | Do not coadminister: Potential for reduced levels of CAB | Potential decrease in antiretroviral efficacy |
Not studied |
Not studied |
Contraindicated. Use alternative agents. |
|
| Bictegravir Enzalutamide 72 | Red: Avoid combination | Do not coadminister: Potential for reduced levels of BIC | Potential decrease in antiretroviral efficacy |
Contraindicated. Use alternative agents. |
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| Fostemsavir Enzalutamide 18 | Red: Avoid combination | Do not coadminister: Potential for reduced levels of temsavir | Potential decrease in antiretroviral efficacy |
Contraindicated. Use alternative agents. |

