| Interaction Color Code | Clinical Bottom Line | Clinical Effects | Drug 1 effect | Drug 2 dose | Drug 2 effect | Management | |
|---|---|---|---|---|---|---|---|
| Atazanavir Rosiglitazone 807 | Green: Administer standard doses | Administer standard doses | Potential for increased rosiglitazone adverse effects |
4 mg x 1 | Rosiglitazone AUC increased 35% |
Monitor for anti-diabetic agent efficacy if using unboosted atazanavir, and toxicity if using unboosted atazanavir |
|
| Atazanavir Rosiglitazone 806 | Green: Administer standard doses | Administer standard doses | Potential decreased glycemic control |
4 mg x 1 | Rosiglitazone AUC decreased 17% |
Monitor for anti-diabetic agent efficacy if using unboosted atazanavir, and toxicity if using unboosted atazanavir |
