Pantoprazole

Drug Class or Subclass

Gastrointestinal secretion and motility agents

Proton pump inhibitors

Generic

Pantoprazole

Brand Name

Protonix

Import ID

170

Displaying 1 - 2 of 2

	Interaction Color Code	Clinical Bottom Line	Clinical Effects	Drug 1 effect	Drug 2 dose	Drug 2 effect	Management
Atazanavir Pantoprazole 786	Yellow: Adjust dosing	Adjust dosing to avoid reduced levels of atazanavir	Potential loss of antiretroviral efficacy				Do not coadminister PPIs with unboosted atazanavir. PPIs may be administered 12 hours before atazanavir when boosted with ritonavir or cobicistat, in treatment naive patients. Doses should not exceed the equivalent of omeprazole 20 mg daily. PPIs are not recommended for treatment experienced patients.
Atazanavir Pantoprazole 776	Yellow: Adjust dosing	Adjust dosing to avoid reduced levels of atazanavir					Administer proton pump inhibitor at least 12 hours before atazanavir / cobicistat. Proton pump inhibitors should not exceed a dose equivalent to omeprazole 20 mg daily in protease inhibitor naive patients. Proton pump inhibitors are not recommended in protease inhibitor experienced patients.

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