Generic
Esomeprazole
Brand Name
Nexium
Import ID
166
Esomeprazole
| Interaction Color Code | Clinical Bottom Line | Clinical Effects | Drug 1 effect | Drug 2 dose | Drug 2 effect | Management | |
|---|---|---|---|---|---|---|---|
| Rilpivirine Esomeprazole 123 | Red: Avoid combination | Do not coadminister: Reduced levels of rilpivirine | Decreased rilpivirine effects |
Contraindicated. Use alternative agents. |
|||
| Atazanavir Esomeprazole 777 | Yellow: Adjust dosing | Adjust dosing to avoid reduced levels of atazanavir | Potential loss of antiretroviral efficacy |
Do not coadminister PPIs with unboosted atazanavir. PPIs may be administered 12 hours before atazanavir if boosted with ritonavir or cobicistat, in treatment naive patients. Doses should not exceed the equivalent of omeprazole 20 mg daily. PPIs are not recommended for treatment experienced patients. |
