| Interaction Color Code | Clinical Bottom Line | Clinical Effects | Drug 1 effect | Drug 2 dose | Drug 2 effect | Management | |
|---|---|---|---|---|---|---|---|
| Lenacapavir Verapamil | Yellow: Adjust dosing | Minimal data to guide interaction: weigh risks and benefits of using this combination | Potential increased risk of verapamil adverse effects |
If coadministering, monitor for cardiac medication adverse effects (e.g. hypotension) |
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| Darunavir Verapamil 1024 | Orange: Minimal data to guide interaction | Minimal data to guide interaction: weigh risks and benefits of using this combination | Potential for increased risk of verapamil adverse effects |
If coadministering, monitor verapamil adverse effects |
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| Etravirine Verapamil 573 | Orange: Minimal data to guide interaction | minimal data to guide interaction: weigh risks and benefits of using this combination | Potential decreased verampil efficacy |
If coadministring, titrate verapamil based on clinical response |
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| Elvitegravir Verapamil 262 | Orange: Minimal data to guide interaction | Minimal data to guide interaction: weigh risks and benefits of using this combination | Potential for increased risk of verapamil adverse effects |
If coadministering use with caution and monitor ECG |
