Generic
Rivaroxaban
Brand Name
Xarelto
Import ID
140
Rivaroxaban
| Interaction Color Code | Clinical Bottom Line | Clinical Effects | Drug 1 effect | Drug 2 dose | Drug 2 effect | Management | |
|---|---|---|---|---|---|---|---|
| Lenacapavir Rivaroxaban | Yellow: Adjust dosing | Minimal data to guide interaction: weigh risks and benefits of using this combination | Potential increased risk of bleeding |
Use with caution. Monitor for rivaroxaban adverse effects (e.g. bleeding). Avoid coadministration in persons with renal impairment (CrCL 15 - 80 ml/min) due to increased risk of bleeding. |
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| Ritonavir Rivaroxaban 1091 | Orange: Minimal data to guide interaction | Minimal data to guide interaction: risks likely to outweigh benefits | Potential for increased risk of bleeding |
Not studied |
Not studied (may increase rivaroxaban levels) |
Avoid combination and use alternative anticoagulant |
|
| Darunavir Rivaroxaban 990 | Orange: Minimal data to guide interaction | Minimal data to guide interaction: risks likely to outweigh benefits | Potential for increased bleeding risk |
Use alternative agents |
|||
| Darunavir Rivaroxaban 967 | Orange: Minimal data to guide interaction | Minimal data to guide interaction: risks likely to outweigh benefits | Potential for increased bleeding risk |
Avoid combination; use alternative anticoagulant |
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| Atazanavir Rivaroxaban 864 | Orange: Minimal data to guide interaction | Minimal data to guide interaction: weigh risks and benefits of using this combination | Potential for increased risk of bleeding |
Consider using alternative agents |
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| Elvitegravir Rivaroxaban 223 | Orange: Minimal data to guide interaction | Minimal data to guide interaction: risks likely to outweigh benefits | Potential for increased risk of bleeding |
Avoid combination and use alternative anticoagulant |
