Generic
Propafenone
Brand Name
Rythmol
Import ID
137
Propafenone
| Interaction Color Code | Clinical Bottom Line | Clinical Effects | Drug 1 effect | Drug 2 dose | Drug 2 effect | Management | |
|---|---|---|---|---|---|---|---|
| Lenacapavir Propafenone | Yellow: Adjust dosing | Minimal data to guide interaction: weigh risks and benefits of using this combination | Potential increased risk of propafenone adverse effects |
Consider using alternative antiarrhythmic or ARV. If coadministering, monitor for propafenone adverse effects. |
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| Ritonavir Propafenone 1081 | Red: Avoid combination | Do not coadminister: Potential for increased levels of propafenone | Increased propafenone effects (eg, cardiac arrhythmias) |
Not studied |
Not studied (may increase propafenone levels) |
Use alternative agents |
|
| Darunavir Propafenone 921 | Red: Avoid combination | Do not coadminister: Increased levels of propafenone | Potential for increased risk of propafenone adverse effects |
Use alternative agents |
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| Atazanavir Propafenone 859 | Orange: Minimal data to guide interaction | Minimal data to guide interaction: weigh risks and benefits of using this combination | Potential for increased propafenone effects (eg, cardiac arrhythmias) |
If coadministering use with caution. Monitor for toxicity. |
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| Elvitegravir Propafenone 268 | Orange: Minimal data to guide interaction | Minimal data to guide interaction: weigh risks and benefits of using this combination | Potential for increased risk of propafenone adverse effects |
If coadministering use with caution and monitor for propafenone toxicity. Consider therapeutic drug monitoring and ECG |
