| Interaction Color Code | Clinical Bottom Line | Clinical Effects | Drug 1 effect | Drug 2 dose | Drug 2 effect | Management | |
|---|---|---|---|---|---|---|---|
| Lenacapavir Ivabradine | Red: Avoid combination | Do not coadminister: potentially increased levels of ivabradine | Potential increased risk of ivabradine adverse effects |
Use alternative agents. |
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| Darunavir Ivabradine 933 | Red: Avoid combination | Do not coadminister: Potential for increased ivabradine levels | Potential for increased risk of ivabradine adverse effects (e.g. prolonged QT, cardiac arrythmias) |
Use alternative agents |
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| Elvitegravir Ivabradine 208 | Red: Avoid combination | Do not coadminister: Potential for increased levels of ivabradine | Potential for increased risk of ivabradine adverse effects |
Contraindicated. Use alternative agents. |
