Generic
Simeprevir
Brand Name
Olysio
Import ID
106
Simeprevir
| Interaction Color Code | Clinical Bottom Line | Clinical Effects | Drug 1 effect | Drug 2 dose | Drug 2 effect | Management | |
|---|---|---|---|---|---|---|---|
| Rilpivirine Simeprevir 651 | Green: Administer standard doses | Administer standard doses | Rilpivirine Cmin increased 25% |
150 mg daily x 11 days | No significant change |
||
| Elvitegravir Simeprevir 199 | Red: Avoid combination | Do not coadminister: Potential for increased levels of simeprevir | Potential for increased simeprevir toxicity |
Use alternative agents |
