| Interaction Color Code | Clinical Bottom Line | Clinical Effects | Drug 1 effect | Drug 2 dose | Drug 2 effect | Management | |
|---|---|---|---|---|---|---|---|
| Darunavir Risperidone 887 | Yellow: Adjust dosing | Adjust dosing to avoid increased levels of risperidone | Potential for increased risk of risperidone adverse effects |
If coadministering, dose reduction may be necessary |
|||
| Elvitegravir Risperidone 171 | Yellow: Adjust dosing | Adjust dosing to avoid increased levels of risperidone | Potential for increased risk of risperidone adverse effects |
Initiate lowest starting dose or decrease current dose of antipsychotic. Monitor efficacy and adverse effects. |
