| Interaction Color Code | Clinical Bottom Line | Clinical Effects | Drug 1 effect | Drug 2 dose | Drug 2 effect | Management | |
|---|---|---|---|---|---|---|---|
| Etravirine Lumefantrine 564 | Orange: Minimal data to guide interaction | Minimal data to guide interaction: weigh risks and benefits of using this combination | Decreased antimalarial effects |
No significant change |
artemether / Lumefantrine 80 / 480 mg | Lumefantrine AUC decreased 13% |
If coadministering, monitor for anti-malarial efficacy. |
