Dexamethasone

Drug Class or Subclass
Generic
Dexamethasone
Brand Name
Decadron
Import ID
68
Displaying 1 - 5 of 5
Interaction Color Code Clinical Bottom Line Clinical Effects Drug 1 effect Drug 2 dose Drug 2 effect Management
Rilpivirine (IM) Dexamethasone Red: Avoid combination Do not coadminister: Potential for reduced levels of rilpivirine

Decreased rilpivirine effects if dexamethasone is given as more than a single-dose treatment

Use alternative agents if therapy requires more than a single dose treatment of dexamethasone.

Lenacapavir Dexamethasone Yellow: Adjust dosing Minimal data to guide interaction: weigh risks and benefits of using this combination

Potential increased risk of corticosteroid adverse effects (e.g. Cushing's syndrome and adrenal supression).

If co-administering, initiate with the lowest starting dose and titrate to clinical effect. Do not use doses of dexamethasone > 16 mg. Monitor for dexamethasone-related adverse effects.

Darunavir Dexamethasone 1031 Orange: Minimal data to guide interaction Minimal data to guide interaction: weigh risks and benefits of using this combination

Potential loss of antiviral efficiacy

Not studied

Monitor viral load if extended dexamethasone use. Consider alternative corticosteroid for long-term use.

Elvitegravir Dexamethasone 278 Orange: Minimal data to guide interaction Minimal data to guide interaction: weigh risks and benefits of using this combination

Potential loss of antiviral efficacy

Monitor viral load if extended dexamethasone use. Consider alternative corticosteroid for long-term use.

Bictegravir Dexamethasone 84 Orange: Minimal data to guide interaction Minimal data to guide interaction: weigh risks and benefits of using this combination

Potential decrease in bictegravir levels and antiretroviral efficacy after chronic administration

If coadministering, monitor for antiretroviral efficacy. If using long-term, consider using alternative corticosteroid or antiretroviral.