| Interaction Color Code | Clinical Bottom Line | Clinical Effects | Drug 1 effect | Drug 2 dose | Drug 2 effect | Management | |
|---|---|---|---|---|---|---|---|
| Ritonavir Cetirizine 1068 | Green: Administer standard doses | Administer standard doses | Not studied |
10 mg daily | Cetirizine AUC increased 42%; half-life: increased 52%; clearance: decreased 29%; Cmax no significant change |
||
| Efavirenz Cetirizine 420 | Green: Administer standard doses | Administer standard doses | No significant change |
10 mg x 1 dose | Cetirizine Cmax decreased 24% |
||
| Efavirenz Cetirizine 419 | Green: Administer standard doses | Administer standard doses | No significant change |
10 mg x 1 dose | Cetirizine Cmax decreased 24% |
