Amitriptyline

Drug Class or Subclass

Antidepressants

Tricyclic antidepressants

Generic

Amitriptyline

Brand Name

Elavil

Import ID

39

Displaying 1 - 3 of 3

	Interaction Color Code	Clinical Bottom Line	Clinical Effects	Drug 1 effect	Drug 2 dose	Drug 2 effect	Management
Ritonavir Amitriptyline 1055	Green: Administer standard doses	Administer standard doses	Increased amitriptyline effects (eg, dry mouth, hypotension, confusion)	Not studied		Not studied (may increase amitriptyline levels)	Monitor and adjust amitriptyline as indicated
Darunavir Amitriptyline 1003	Orange: Minimal data to guide interaction	Minimal data to guide interaction: weigh risks and benefits of using this combination	Potential for increased risk of amitriptyline adverse effects				If coadministering, initiate amitriptyline at low dose. Monitor for CNS and cardiovascular effects.
Elvitegravir Amitriptyline 150	Yellow: Adjust dosing	Adjust dosing to avoid increased levels of amitriptyline	Potential for increased risk of amitriptyline adverse effects				If coadministering initiate amitriptyline at lowest dose. Monitor response and titrate according to efficacy and adverse effects.

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