Generic
Bedaquiline
Brand Name
Sirturo
Import ID
14
| Interaction Color Code | Clinical Bottom Line | Clinical Effects | Drug 1 effect | Drug 2 dose | Drug 2 effect | Management | |
|---|---|---|---|---|---|---|---|
| Lenacapavir Bedaquiline | Yellow: Adjust dosing | Minimal data to guide interaction: weigh risks and benefits of using this combination | Potential for increased bedaquiline levels |
Consider alternative agents. If coadministering, monitor LFTs and ECG. |
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| Darunavir Bedaquiline 925 | Red: Avoid combination | Do not coadminister: Potential for increased bedaquiline levels | Potential for increased risk of bedaquiline adverse effects |
Avoid combination and use alternative agents. If coadministering, monitor liver function and QTc interval |
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| Etravirine Bedaquiline 540 | Red: Avoid combination | Do not coadminister: Potential for reduced levels of bedaquiline | potentially reduced levels of bedaquiline |