| Interaction Color Code | Clinical Bottom Line | Clinical Effects | Drug 1 effect | Drug 2 dose | Drug 2 effect | Management | |
|---|---|---|---|---|---|---|---|
| Darunavir Terazosin 1005 | Orange: Minimal data to guide interaction | Minimal data to guide interaction: weigh risks and benefits of using this combination | Potential for increased risk of terazosin adverse effects |
If coadministering, initiate at lowest dose and titrate while monitoring for clinical response / adverse effects |
|||
| Elvitegravir Terazosin 174 | Yellow: Adjust dosing | Adjust dosing to avoid increased levels of terazosin | Potential for increased terazosin adverse effects |
Initiate low dose terazosin and titrate dose according to efficacy and adverse effects. |
