Lenacapavir Darunavir/cobicistat

Sunlenca Product Label

Interaction Color Code
Clinical Bottom Line
Administer standard doses
Drug 1
Drug 1 dose
300 mg orally x 1
Drug 1 effect

AUC increased 94%; Cmax increased 130%

Drug 2 dose
800/150 mg once daily (in fed state)
Drug 2 effect

Not reported

Mechanism
Inhibition of CYP3A4 by cobicistat
Clinical Effects

No clinically significant effect expected