Interaction Color Code
Clinical Bottom Line
Minimal data to guide interaction: risks likely to outweigh benefits
Drug 1
Drug 1 dose
200 mg daily TID
Drug 1 effect
Decreased ritonavir levels)
Drug 2
Drug 2 dose
350 mg BID
Drug 2 effect
Not studied (may increase carbamazepine levels)
Clinical Effects
Increased carbamazepine effects; decreased ritonavir effects
Management
Avoid combination and use alternative agents. If coadministering monitor carbamazepine levels and adjust as indicated. Monitor antiviral efficacy
Alternative Agents
Gabapentin Lamotrigine Tiagabine Topiramate
Import ID
1088
