Interaction Color Code
Clinical Bottom Line
Do not coadminister: Reduced levels of ritonavir
Drug 1
Drug 1 dose
500 mg Q12H x 20 days
Drug 1 effect
Ritonavir AUC decreased 35%; Cmax decreased 25%
Drug 2
Drug 2 dose
300 mg or 600 mg x 10 days
Clinical Effects
Decreased ritonavir effects
Management
Use alternative agents
Alternative Agents
Rifabutin
Import ID
1085
