Interaction Color Code
Clinical Bottom Line
Adjust dosing to avoid reduced levels of methadone
Drug 1
Drug 1 dose
100 mg BID x 7 days
Drug 2
Drug 2 dose
Stable methadone dose
Drug 2 effect
No significant effect
Management
If coadministering monitor for signs and symptoms of methadone withdrawal. Some patients may require an increased methadone dose
Import ID
1053
