Interaction Color Code
Clinical Bottom Line
Adjust dosing to avoid increased levels of maraviroc
Drug 1
Drug 1 dose
100 mg BID
Drug 2
Drug 2 dose
100 mg BID
Drug 2 effect
Maraviroc AUC increased 161%; Cmin increased 355%; Cmax increased 28%
Clinical Effects
Increased maraviroc effects
Management
Reduce dose of maraviroc to 150 mg BID with strong CYP3A4 inhibitors
Import ID
1042
