Darunavir CsA 1011

Prezista label

Clinical Bottom Line
Minimal data to guide interaction: weigh risks and benefits of using this combination
Drug 1
Drug 1 effect

Not studied

Drug 2
Drug 2 effect

Not studied (may increase cyclosporine levels)

Clinical Effects

Potential for increased risk of cyclosporine adverse effects (supratherapeutic immunosuppression, renal toxicity)

Management

If coadministering, initiate lower dose of immunosuppressant, monitor concentrations and toxicity, consult with specialist, and adjust dose as necessary

Import ID
1011